Objective: Pearly penile papules are asymptomatic, benign growths distributed around the corona of the penis that can frequently be a source of significant psychological distress for the patient. Various treatment options are limited mainly by their complications. Design: Two case reports and a review of the literature. Setting: University academic setting. Participants: Two subjects of skin types I and V. Measurements: Visual inspection and photographs were used to determine clearance. Results: Two cases of pearly penile papules that were successfully treated using a fractionated CO2 laser. Conclusion: The fractionated CO2 laser is a well-tolerated treatment for pearly penile papules. Importantly, this modality is useful even in darker skin types.
Ectopic sebaceous glands and lichen nitidus are both commonly located on the penile shaft and can thus be eliminated from diagnosis. Furthermore, ectopic sebaceous glands are yellowish in color and can often discharge a cheese-like material. On the other hand, lesions of lichen nitidus tend to be flat-topped and are often polygonal in shape. In cases in which the diagnosis is uncertain, a biopsy can be performed, as pearly penile papules have a unique microscopic anatomy.5
While lumps on the penis are frequently a source of great anxiety for the patient, if it is unclear whether the lesion is a normal variant or not, there is usually no harm in asking the patient to return for review. In some cases, it is necessary to refer to a more experienced colleague, a sexual health service or dermatologist to assist with diagnosis. A second opinion is often more efficient and preferable to the patient than a biopsy or a trial of treatment.
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What should you do about a pimple on the penis? Pimples can occur anywhere on the body, including the genitals, and a pimple on the penis can have a range of causes. Knowing the signs of an STD can help people determine when to see a doctor or whether treatment is not needed. Learn more about the causes of a pimple on the penis, and the treatment options, here. Read now
Tea tree oil is directly extracted from the Melaleuca alternifolia tree leaves and is commonly used oil for skin ailments. The oil is well regarded by the scientific community in treatments for acne and skin rashes. Even the American cancer Society found the oil was useful while treating skin injuries and avoiding putrefaction. Studies have shown the oil is toxic when consumed and must not be applied to skin if the concentration is greater than 5%.

A 16-year-old white adolescent boy (Fitzpatrick skin type 1) presented with a 2-year history of progressive development of multiple, asymptomatic, fleshy, tiny papules around the coronal rim of the glans penis. The patient was uncircumcised. His past health was unremarkable, and there was no history of venereal exposure. He was anxious and embarrassed by the lesions.

It is a rather simple procedure, with little to no discomfort during the recovery. A dermatologist uses the CO2 laser to carefully vaporize the bumps. Your doctor will numb the area first with topical lidocaine only. No injections are needed to numb the treatment area. Afterward, there will be some scabbing and swelling, but don’t worry – you should be back to normal in a week or two. CO2 laser ablation is the safest and most effective method of treatment.

In short, PPP is an indication that you are unique and naturally gifted with a studded penis. You can live with, or you can treat it. The top advice is to learn to love life with it. Don't think of removal if your partner accepts it because it adds to the sexual pleasure. If you still want to get rid of it, then check the treatment section later in this article.
Because of the benign nature of PPP as well as their regression with age, treatment is generally reserved for patients who suffer extensive embarrassment or concern. Cryotherapy and lasers have been reported in such cases. One study performed two sessions of cryotherapy in four patients and cleared 80% to 90% of lesions without complications (Ocampo-Candiani & Cueva-Rodriguez, 1996). Another case report of a patient with dark skin described similarly successful results with no pigmentation changes and no lesion recurrence after 2 years (Porter & Bunker, 2000).
Ectopic sebaceous glands and lichen nitidus are both commonly located on the penile shaft and can thus be eliminated from diagnosis. Furthermore, ectopic sebaceous glands are yellowish in color and can often discharge a cheese-like material. On the other hand, lesions of lichen nitidus tend to be flat-topped and are often polygonal in shape. In cases in which the diagnosis is uncertain, a biopsy can be performed, as pearly penile papules have a unique microscopic anatomy.5
A diagnosis of pearly penile papules can be obtained from a dermatologist or similarly trained physician. The differential diagnosis (elimination of possible alternative conditions) includes condyloma acuminata (genital warts), molluscum contagiosum, ectopic sebaceous glands, and lichen nitidus. Condyloma acuminata are most important to rule out because unlike pearly penile papules, they are less uniform in shape and size, appear to be more wart-like, and might change in appearance over time.5 In addition, genital warts are not typically arranged in neat circular rows surrounding the corona of the glans, as are pearly penile papules. Lesions of molluscum contagiosum tend to be larger in size and marked by navel-like depressions, sometimes with a pink hue.
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I treat PPP with radiofrequency ablation using the Ellman machine.  We use topical numbing cream and treatment is virtually painless.  With a gentle technique, I am able to vaporize and eliminate these small papules.  Results are seen immediately and recovery is rapid.  My patients have been very pleased with the results.  I often have patients fly in from out of state for treatment.
A thousand questions may be running through your mind right now. What in the world is that bump? Did I catch a disease? Do I have cancer? Stop. Take a deep breath. Relax. While it can be unnerving to find bumps on your penis, there may be a simple and benign explanation. Though you should have it checked out by a doctor just to be sure, your diagnosis is likely pearly penile papules, scientifically referred to as hirsuties papillaris genitalis. What? Despite the funny alliteration, finding these bumps can be really scary and an uncomfortable topic to bring up to your doctor. But, once you know what they are, you can figure out what you want to do about them.
Pearly penile papules (commonly referred to as “PPP”) are typically benign (non-cancerous) growths found circumferentially in a single or double row around the head of the penis. The shape, size, and color of PPP can vary between individuals, but they are most often round, 1-2 mm in diameter, and pink, flesh-colored, or translucent. All lesions on a single patient tend to be identical. Lesions first appear within the second or third decade of life.
Pearly penile papules (PPP) are common, benign lesions that appear on the corona of the glans penis during adolescence or early adulthood. Despite their benign nature, PPP are known to cause significant distress because of their resemblance to sexually transmitted infections such as condyloma acuminata. PPP can be clinically distinguished based on their uniform, dome-shaped papules that orient in one to two rows around the glans penis. There is no association between PPP and sexually transmitted infections, and treatment is generally reserved for patients with excessive concern. Physicians should be aware of this distinction in order to adequately reassure anxious patients. For patients who still desire treatment after counseling, cryotherapy and laser therapy represent two reliable treatment options with low rates of recurrence.
They most commonly appear in a row, somewhat like a string of pearls, which is why they are called pearly papules. Men who’ve suffered from this skin ailment know these papules look gruesome and tend to worry about their sexual health. However, the papules are fairly common and hardly serious. They pose no health risks and are completely painless. About 20% of men are expected to develop some form of PPP in their lifetime. It is also unrelated to sexual activity or personal hygiene.
Pearly penile papules (PPP) are small, benign (non-cancerous) growths. PPP can be pink, white, yellow, or (rarely) translucent in color. They’re normally very small, ranging from 1-2mm wide by 1-4mm long. The shape, color, and size can vary between people, but all the papules that one person has will look the same. The papules are usually found in a single or double row on or around the head of the penis.
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