Ablation using carbon dioxide laser, [10, 11, 12] electrodesiccation with curettage, and excisional surgery reportedly have successfully eliminated pearly penile papules. Recent technological advancements in lasers have resulted in promising outcomes using newer fractional ablative approaches, [13, 14] including fractionated carbon dioxide lasers. [15] Successful treatment with pulsed dye laser has been reported, [16] as has treatment with erbium:yttrium-aluminium-garnet (Er:YAG) laser. [17]

Although it is not related to any pathological condition, hirsuties papillaris genitalis is occasionally mistaken for HPV warts.[15] There are also home remedies for "curing" it, despite the fact that the papules are neither infectious nor detrimental to one's health and may have beneficial functions.[6][7] Some of the "home remedies" found on the Internet and elsewhere use mild ointments or creams to soften the papules, but others are physically dangerous techniques for papule removal which can result in permanent genital mutilation.[1]
If you ever notice any bumps, discoloration, or other unusual feature develop on or around your genitals, see a doctor to get a diagnosis. Some changes, such as pearly penile papules, are completely benign. But any change can cause some anxiety, so don’t hesitate to get checked out. A urologist is a doctor who specializes in the health of the male reproductive organs and in conditions affecting the male or female urinary system. However, going to your primary care doctor is often a good first step.

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On dermoscopy, PPP appear white or pink in a cobblestone or grape-like pattern with each papule containing central dotted or comma-shaped vessels (Figure 1; Ozeki, Saito, & Tanaka, 2008; Watanabe, Yoshida, & Yamamoto, 2010). This vessel architecture is nonspecific and can also be seen in condyloma (Watanabe et al., 2010). Unlike warts, however, PPP do not have desquamation, which is seen as an irregular reflection on dermoscopy (Ozeki et al., 2008).
I’m pretty sure I’ve got pearly penile papules. The little pimple like things look exactly like it’s described here and yes, my girlfriend freaking hates them. She hasn’t had sex with me ever since I told her about it and the lack of sex is driving me insane. It was stupid of me to tell her that, but she would have found out on her own eventually anyways. I’ve got two choices. I either breakup with my girlfriend and go out with a girl who is okay with it, or I get rid of it. Personally I’m fine living with ppp.
Pearly Penile Papules removal methods include surgical,over the counter creams or gels & home remedies .You can cure ppp completely & permanently using the removal methods given here .Sufferers of PPP can find here a few suggestions and advices based on detailed researches regarding the various methods of treatment for removal of Pearly Penile Papules. You can get rid of your PPP completely provided you know the proper method of treatment. There is no oral medication for curing Pearly Penile Papules.
Pearly penile papules (PPP), which are angiofibroma lesions found at the base of the glans penis, are benign growths that affect about 10% of men. A dermatologist can safely and effectively treat these for you using a variety of techniques such as laser, electrodesiccation, or other destructive methods. I use a special anesthetic so that there is ZERO discomfort. I have seen people treat their PPP lesions themselves with horrific results and significant pain and much cost to try and fix the markings and scarring. Do not attempt to treat yourself, you will regret it. ~ Dr. Benjamin Barankin, Toronto Dermatology Centre

When diagnosis is uncertain, a biopsy may be performed to rule out other conditions.1 Several modes of therapy are used for treating pearly penile papules, including cryotherapy, electrodesiccation, podophyllin, curettage and carbon dioxide laser ablation. Ablation using intermittent- or continous-mode carbon dioxide laser is reported to have the best outcome cosmetically. Treatment should be reserved for patients who are highly distressed by the appearance of this very common and benign entity.2
Some men are often too embarrassed to consult their doctor about pearly penile papules, which leads men to try over-the-counter or web-based creams, lotions, and DIY home remedies. Dr. Groff warns that by using home remedies, men risk making their condition worse by developing scarring issues, inflammation, loss of sensation, infection, bruising, numbness, and other serious side effects. Home remedies can cause permanent damage.
The best advice for an individual with pearly penile papules for whom surgery is not a viable consideration is simply to love your body. Pearly penile papules are not going to scare away a partner who genuinely cares for you. If you happen to encounter such a person, he or she was certainly not worth the time investment. In the meantime, accept that you are among a select group of rare anatomical variants and take pride in being special. Some partners of individuals with pearly penile papules even claim that the papules enhance their receptive sexual sensations. While it is understandable to feel some anxiety over a physical “abnormality,” especially when it affects such a delicate region of the body, acceptance and respect for oneself is inarguably the healthiest (and most cost-effective) mode of treatment.
According to a study published in the International Journal of STD & AIDS, over one-third of men with pearly penile papules had been concerned or worried about their lesions, and about 1 in 4 said they were embarrassed of them. So it’s not really surprising that 14 percent of men with small lesions (less than 1 mm) and 75 percent with larger ones (greater than 1 mm) wanted to have them removed.
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Home remedies for PPP absolutely do not work. The ads that you see on for home remedies are scams. Many of these scam artists have copied my before and after photos and use them in their ads. Do not waste your time and money. I have also seen many cases of scarring and disfigurement from these home remedies and also from treatment by inexperienced or unlicensed practioners.
Molluscum contagiosum appear as small papules with a central depression or umbilication. They are caused by a member of the poxvirus family, molluscum contagiosum virus (MCV). Molluscum contagiosum are commonly acquired by children from non-sexual skin contact, often during bathing or swimming with other infected children. In adults however, sexually transmitted molluscum may be seen on or near the genitals (Figure 7). The virus has a self limiting course over a period of months, but treatment with cryotherapy is often recommended to prevent the spread of MCV to others.11,12

Pearly penile papules (PPP) are small, benign (non-cancerous) growths. PPP can be pink, white, yellow, or (rarely) translucent in color. They’re normally very small, ranging from 1-2mm wide by 1-4mm long. The shape, color, and size can vary between people, but all the papules that one person has will look the same. The papules are usually found in a single or double row on or around the head of the penis.